Peritoneal Mesothelioma

Explore the world of peritoneal mesothelioma, its causes, symptoms, diagnosis methods, treatment options, and more in this comprehensive guide. Discover who is at risk and gain insights into staging and prevention.

What Is Peritoneal Mesothelioma?

Peritoneal Mesothelioma

Peritoneal mesothelioma is a rare and aggressive form of cancer that affects the peritoneum, the thin membrane lining the abdomen.

This type of mesothelioma is primarily linked to exposure to asbestos, a mineral once widely used in construction and industrial settings.

In this guide, we will delve into the various aspects of peritoneal mesothelioma, providing clear and concise information for those seeking to understand this condition better.

What Causes Peritoneal Mesothelioma?

The primary cause of peritoneal mesothelioma is exposure to asbestos. Asbestos is a naturally occurring mineral that was extensively used in the past for its fire-resistant properties.

Inhalation or ingestion of asbestos fibers can lead to their accumulation in the peritoneum, triggering the development of cancerous cells over time.

Secondary exposure to asbestos can also contribute to peritoneal mesothelioma. Individuals who have direct contact with asbestos-exposed individuals, such as family members or close friends, may unknowingly inhale or ingest asbestos fibers brought home on contaminated clothing or belongings.

Symptoms of Peritoneal Mesothelioma

Peritoneal mesothelioma symptoms may not manifest until several decades after asbestos exposure. Common symptoms include:

  • Abdominal pain or swelling
  • Unexplained weight loss
  • Changes in bowel habits
  • Fatigue
  • Nausea and vomiting

It is crucial to seek medical attention if experiencing any of these symptoms, especially for those with a history of asbestos exposure.

How Is Peritoneal Mesothelioma Diagnosed?

Imaging Tests

To diagnose peritoneal mesothelioma, doctors may perform imaging tests such as CT scans or MRIs to visualize abnormalities in the abdomen.


A biopsy is a key diagnostic procedure where a small tissue sample is extracted from the affected area for examination under a microscope. This helps confirm the presence of mesothelioma cells.

Staging Peritoneal Mesothelioma

Staging helps determine the extent of cancer spread and guides treatment decisions.

  • Stage I: Limited to the peritoneum
  • Stage II: Involvement of nearby organs
  • Stage III: Spread to lymph nodes
  • Stage IV: Distant metastasis

Who Is at Risk for Peritoneal Mesothelioma?

Occupations at Risk

Certain occupations, such as construction workers, shipyard workers, and asbestos miners, are at higher risk due to occupational asbestos exposure.

Family Members

Those living with asbestos-exposed individuals are also at risk due to potential secondary exposure.

Pre-existing Conditions

Individuals with pre-existing lung conditions may be more susceptible to asbestos-related diseases.

What Is the Treatment for Peritoneal Mesothelioma?


Surgical options include debulking to remove tumors, and in some cases, a complete peritonectomy to remove the peritoneum.


Chemotherapy may be used to shrink tumors before surgery or to control the spread of cancer.

Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

This treatment involves heated chemotherapy directly applied to the abdominal cavity during surgery.


In conclusion, peritoneal mesothelioma is a rare but serious cancer primarily caused by asbestos exposure. Early detection and a multidisciplinary treatment approach can significantly improve outcomes. Understanding the symptoms, risk factors, and available treatments is crucial for individuals at risk or already diagnosed with peritoneal mesothelioma. If you suspect exposure or experience symptoms, consult with a healthcare professional promptly for proper evaluation and guidance.